IIST has a well experienced medical team with a Cheif Medical Consultant, a Medical Officer and paramedical staff. Their service is available to students and staff throughout the working hours on all days. A clinic has been established in the campus with sufficient medicines and equipment to take care of the day medical needs.

IIST has ensured emergency medical care and hospitalization for all its students by entering into a Memorandum of Understanding with M/s Ananthapuri Health Services, one of the leading hosiptal of Thiruvananthapuram city. Every student of IIST also gets a medical insurance coverage upto Rs One Lakh, which is funded from the Assistanceship Fee granted by the Department of Space.