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  • 6:45 AM, Saturday, 31 Oct 2020

Department of Chemistry
     
Sandhya K.Y.
Associate Professor
 
Office
Tel:+91-471-2568551
Fax:
Email:sandhya@iist.ac.in













Education
  • Ph.D. (Chemistry) NIIST (Regional Research Laboratory, RRL), Thiruvananthapuram.
  • M.Sc. (Chemistry) M. S. University, Tirunelveli.

Course Offered

Undergraduate Chemistry Courses:

2009 to till date

Chemical Kinetics & Spectroscopy, Electrochemistry & Corrosion; Polymer chemistry, Electrochemical Energy Systems, Organic Chemistry

Post Gradute Chemistry Courses:

  • Electrochemical Energy Systems
  • Material Characterization Techniques
  • Nanoscience & Technology

Experience
  • Scientist C., SCTIMST, Poojappura, Thiruvananthapuram
  • Sr. Lecturer: Amrita School of Engineering, Bangalore, Lecturer: Govt. Women’s College, Thiruvananthapuram , Noorul Islam University

Research Work / Area

Postdoctoral Fellow

Liquid Crystal Division, Raman Research Institute, Bangalore.

Robert Wood Johnson Medical School-UMDNJ, USA

Areas of Research:

  • Liquid Crystalline Polymers
  • Nonlinear Optical Polymer
  • Biomaterials for Tissue Engineering
  • Dye Sensitized/Organic Solar Cells
  • Self Assembled Materials

Awards
  • Univ. First Rank (Gold Medal) for M.Sc.
  • NET (CSIR-JRF)
  • GATE (Graduate Aptitude Test in Engineering)
  • Best Poster Award for Vijendra Kumar for Super hydrophobic materials based on Calcium carbonate nanoparticles @ MACRO 2013, IISc, Bangalore

My Citations: http://scholar.google.co.in/citations?hl=en&user=o2h77SwAAAAJ

Ph.D. Student:
1. Muhammed Mukthar Ali:  Materials for Dye sensitized/Organic Solar Cells
2. Aswathi Nair: Self Assembled Materials

B.Tech Project Student:
Anurudha Shukla: TiO2-carbon based composites for dye sensitized solar cells. (Completed)

M.Tech Project Student:
Vijendra Kumar:Super hydrophobic materials based on polyurethane for coating applications in Collaboration with VSSC. (Completed).
Dhanya, C Corrosion Studies of Copper in presence of Sulfur and its prevention in collaboration with VSSC.(Completed)

@013

Electrochemistry and Corrosion

Infrared Spectroscopy

Text Books:

Engineering Chemistry R. Gopalan Engineering Chemistry Jain & Jain

References:

Electrochemistry by Philip Reiger

Principles of Corrosion Science and Engineering by Zaki Ahmad

Applications of Organic Spectroscopy John R Dyer

Course Plan for Chemical Kinetics and Spectroscopy, part of CH 111 (2012)
Chemical Kinetics
Lecture 1-2

Basic concepts-reaction rate, rate laws, reaction order, rate constant; Measurement of reaction rates: isolation method, method of initial rates, Problems.

Lecture 2-3

Differential and Integrated rate law expressions: First, Second (type I and type II); half lives; Arrhenius equation: temperature dependence of reaction rate, Problems.

Lecture 3-4

Rate laws: Reaction mechanisms, Overall reaction and elementary reactions, factors affecting reaction rate, collision theory and rate determining step(s).

Lecture 5-6

Derivation of rate laws for reactions from their mechanisms/elementary reaction steps. Problems.

Lecture 7-9

Kinetics of Complex reactions with examples: Pseudo steady state hypothesis (PSSH)  Derivation of rate law from mechanisms for decomposition of N2O5, formation of NOBr and othr reactions-Derivation of rate law using mechanisms with  known and unknown rate determining steps.

Lecture 10-11

Kinetics of radical chain reactions (Dissociation of Acetaldehyde, Formation of hydrogen bromide)

Lecture 12

Enzyme catalysis and kinetics

Text Book:
  1. P.W Atkins and J.de Paula, Atkins’ Physical Chemistry, 8th ed. Oxford Univ. Press, 2007
Reference:
  1. K. J. Laidler, Chemical Kinetics, Third edition, Pearson Education, 2005
  2. T. Engel and P. Reid, Physical Chemistry, Pearson Education, 2006
Spectroscopic techniques
Introduction:(1h)

Importance, applications, basic concepts; electromagnetic spectrum, types of energies in molecules, regions of the spectrum, different spectroscopic techniques.

Ultra-violet and visible spectroscopy:(4h)

Bonding and antibonding orbitals, types of electronic transitions, Beer’s law, Lambert’s law, instrumentation

Chromophore, auxochrome, absorption and intensity shift, solvent effect, conjugated dienes, Woodward-Fieser rules for calculating absorption maximum, applications

Infra-red spectroscopy:(4h)

Introduction, molecular vibrations, vibrational frequency, selection rules, factors influencing vibrational frequency

Instrumentation, sampling techniques, finger print region, interpretation of spectra, characteristic group absorptions

Text Books:
  1. Organic Spectroscopy, William Kemp, III edition
  2. Engineering Chemistry, Jain & Jain
References:
  1. Fundamentals of Molecular spectroscopy, CN Banwell
  2. Applications of absorption spectroscopy of organic molecules, John R Dyer
Evaluation:

Surprise test, Quiz, Assignment

Notes:

Tutorials/Problem Solving sessions will be given (the class may be divided into 2 groups for this and the groups will alternatively attend the sessions)

Assessment methods:

Internal (50 % weightage) comprises of Surprise test(s) & Assignments (may be given) totaling to 20% + Quiz I & II (30%)

End semester (50% weightage)

In End Semester:

Weightage for chemical kinetics and spectroscopy combined will be ~ 50 %

Publications:
  1. Mohamed Mukthar Ali and K. Y. Sandhya* Reduced graphene oxide as a highly efficient adsorbent for 1-naphthol and the mechanism thereof RSC Adv. 2014, 4, 51624-31.
  2. Mohamed Mukthar Ali and K. Y. Sandhya* Visible light responsive titanium dioxide-cyclodextrin-fullerene composite with reduced charge recombination and enhanced photocatalytic activity Carbon 2014, 7, 249-257.
  3. Nair S. K., Verma A., Thomas TJ, Chou TC, Gallo MA, Shirahata A, Thomas T. (2007) Synergistic apoptosis of MCF-7 breast cancer cells by 2-methoxyestradiol and bis(ethyl)norspermine. Cancer Letter 250, 311-22.
  4. Vijayanathan, V., Venkateswaran, S., Nair S. K., Verma A., Thomas T. J., Zhu B. T., Thomas T. (2006) Physiologic levels of 2-methoxyestradiol interfere with nongenomic signaling of 17beta-estradiol in human breast cancer cells. Clinical Cancer Research 12, 2038-48.
  5. Veena Vijayanathan, T. J. Thomas, Sandhya Nair, Akira Shirahata, Michael A. Gallo, and Thresia Thomas, Thomas T. (2006) Bending of the estrogen response element by polyamines and estrogen receptors alpha and beta: a fluorescence resonance energy transfer study. Int J Biochem Cell Biol. 38, 1191-1206.
  6. Nair S. K., Thomas TJ, Greenfield NJ, Chen A, He H, Thomas T. (2005) Conformational dynamics of estrogen receptors alpha and beta as revealed by intrinsic tryptophan fluorescence and circular dichroism. Journal of Molecular Endocrinology 35, 211-23.
  7. Chen A.M., Santhakumaran L. M., Nair S. K., Amenta P. S., Thomas T., He H., and Thomas T. J. (2006) Oligodeoxynucleotide nanostructure formation in the presence of polypropyleneimine dendrimers and their uptake in breast cancer cells, Nanotechnology, 17, 5449-60.
  8. Chen A.M., Nair S. K., Thomas, T., Thomas TJ, He, H.X. (2006) Delivery of Therapeutic Oligonucleotides to Breast Cancer Cells with Dendrimer Modified Gold Nanoparticle NSTI Nanotech (Nano Science and Technology Institute), Boston, May 7-11, Technical Proceedings of the nanotechnology Conference and Trade Show, 2, 29-32.
  9. Sandhya Y. K., Pillai C. K. S. and Tsutsumi N. (2004) Stable Polymers for Nonlinear Optics: A Review based on Azobenzene Systems. Progress in Polymer Science 29, 45-74.
  10. Sandhya Y. K. and Pillai C. K. S. (2004) Liquid Crystalline Polyesteramides: Role of nitro groups on the Phase Behavior, Journal of Polymer Science Polymer Physics 42, 1289 – 1298.
  11. Sandhya Y. K., Pillai C. K. S., Sato M. and Tsutsumi N. (2003) Highly Stable Liquid Crystalline Main Chain Polymers Containing Azobenzene Mesogens for Nonlinear Optics: Effect of Liquid-Crystalline phase on NLO Property, Journal of Polymer Science Polymer Chemistry 41, 1527-1535.
  12. Sandhya Y. K., Biji B. and Pillai C. K. S. (2004) Main chain liquid crystalline polymers containing azobenzene mesogen: effect of introduction of kink structures on thermal and phase behavior. J. Applied Polymer Science 91, 1976-82.
  13. Sandhya Y. K., Pillai C. K. S., Sato M. and Tsutsumi N. (2002) Nonlinear optical properties and liquid crystalline behaviour of new polyesters with dipole moments aligned transverse to the backbone. Macromolecular Chemistry and Physics 203, 1126-1134.
  14. Sandhya Y. K., Pillai C. K. S., Sree Kumar K. and Verma K. B. R. (2002) Structural and Dielectric Studies on Poly (l-lithocholic acid). J. Polymer Materials. 19, 303-308.
  15. C K S Pillai, K. Y. Sandhya, J D Sudha and M Swaminathan Influence of hydrogen bonding on the generation and stabilization of liquid crystalline polyesters, poly (esteramide)s and polyacrylates., Pramana 61, 2, August 2003, 417-25.
Patents:
  1. Mohamed Mukthar Ali and K. Y. Sandhya* Novel method for water soluble fullerenes Patent filed 2554/CHE/2013 dated 12/06/2013.
Conferences/Presentations
  • Oral and Poster Presentation by Vijendra Kumar1, Santhosh Kumar KS2*, Sandhya KY1, Reghunadhan Nair CP2 “Silane and Urethane Chemistry to Access Superhydrophobicity in CaCO3 Nanoparticles” at the Conference FAPS-MACRO-2013 held at Indian Institute of Science, Bangalore. (Best Poster award)
  • Poster presentation by Sandhya KY Remya NS, Remya N, Prabha D Nair on “A biodegradable in situ injectable hydrogel based on chitosan and oxidized hyaluronic acid for tissue engineering applications” at Material Research Society (MRS) Fall meeting, Boston, USA Nov 30- Dec 4, 2009, funded by Dept. of Science & Technology.
  • Poster presented by S. Dhanya chandran1, A. Venugopal2, K.Y. Sandhya3, P.K. jayan1, P.  Revindran1 and Koshy M. George1 “Corrosion compatibility studies on copper alloy in hydrocarbon environment and its prevention “at International conference on Corrosion in Infrastructure and chemical Industries (CICI 2012) organized by ITM Universe, Vodadara,  Gujarat, India on Dec 6-8, 2012.
  • Chen AM, S. K. Nair, T. Thomas, H. He, and T.J. Thomas. Antisense Oligonucleotide Nanoparticles and Their Transport in Breast Cancer Cells, 2006 AACR 97th Annual Meeting, April 1-5, 2006.
  • Sandhya K. Nair, Sasha C., T. J. Thomas and Thresia Thomas Selectivity of Genistein Binding to Estrogen Receptor, 2005, AACR Annual Meeting, Anaheim Convention Centre, Anaheim, CA, USA.
  • Oral Presentation: K.Y. Sandhya, T.J. Thomas and Thresia Thomas, Thermal Unfolding of Estrogen Receptor beta in the Presence and Absence of Estrogen Response Element: An intrinsic fluorescence Study, Molecular Biophysics Minisymposium, May 2004, Center of molecular Biophysics and Biophysical Chemistry, wright-Reiman Laboratories, Rutgers, The State Univ of New jersey, Piscataway, New Jersey, USA.
  • Poster Presentation: Sandhya K. Nair, T. J. Thomas and Thresia Thomas Robert Wood Johnson Medical School, New Brunswick, NJ. A polyamine pathway for the action of 2-methoxyestradiol (2-ME2) and synergistic apoptosis of MCF-7 breast cancer cells with 2-ME2 and a polyamine analogue, 2004, AACR Annual Meeting, Orange County Convention Centre, Orlando, Florida, USA.
  • Poster Presentation: Sandhya K. Nair, T. J. Thomas and Thresia Thomas Robert Wood Johnson Medical School, New Brunswick, NJ. Structural studies of estrogen receptor b using intrinsic tryptophan fluorescence: evidence for an intermediate form of unliganded protein, Biophysical Annual Meeting 2004, Baltimore Convention Centre, MD, USA.
  • Oral Presentation: Sandhya, Y. Karunakarannair, Pillai, C. K. S., Sato, M., and Tsutsumi, N., Highly Stable Rigid Azobenzene containing Main Chain Nonlinear Optical Polymers with Liquid Crystalline Phase: Effect of LC Phase on NLO Response.” in the International Seminar on Frontiers of Polymer Science and Engineering during December 9-11, 2002, The Society for Polymer Science, India.
  • Oral Presentation: Sandhya, Y. Karunakarannair, Pillai, C. K. S., ‘New Nonlinear Optical active Liquid Crystalline Polyesters?, at 1) National Seminar on “Advanced Polymeric Materials & Environmental Protection For the New Millenium, 2001? Univ. of Madras, Chennai, India. 2) Spring meeting of JSPS 2001 (Japanese Society of Polymer Science for cooperative research work by Masataka Sato).